The Luxembourg Statistical Society would like to promote the talks by Stephen Seen and Dr. Holly Jane on Design and analysis of COVID vaccine trials : the familiar and the strange organised by the Société Française de Statistique (SFdS). These talks will take place on Friday 3rd December at 5:00 PM and will be hosted online.

Dr. Holly Jane is a biostatistician working on the design and analysis of vaccine studies, with a particular expertise in HIV and COVID prevention and vaccine science. She is co-PI of the Statisics and Data Management Center of the HIV Vaccine Trials Network and a key investigator in the newly-formed USG-funded COVID Prevention Network.

Stephen Senn is consultant Statistician, worked in the pharmaceutical industry, in the National Health Service, further education and medical research, specialized in statistical methods for designing and analysing drug development programmes and clinical trials


Stephen Senn will start by giving a general presentation on the trials performed to evaluate COVID19 vaccines, discussing some choices such as sequential approach, 2:1 allocation, frequentist vs Bayesian.

Then Dr. Holly Janes will go deeper on some aspects such as choosing appropriate endpoints and long-term-assessment of vaccine efficacy with emergence of new variants.

Practical information

Date: 3 December 2021
Time: 17:00
Place: online
Fee: free
Registration: please register on SFdS website

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